Etidronic Acid
This bisphosphonate medication slows bone breakdown by inhibiting osteoclasts, the cells responsible for dissolving bone tissue. It is used to treat Paget's disease and to prevent bone loss in certain conditions.
Moleküler Ağırlık
206,0300 g/mol
LogP
-3,70
TPSA
135,00 Ų
Lipinski RO5
Geçer
Terapötik Alanlar
Etki Mekanizması
Binds to hydroxyapatite crystals in bone, inhibiting osteoclast-mediated bone resorption by disrupting the mevalonate pathway within osteoclasts. This reduces bone turnover and increases bone mineral density.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to hydroxyapatite crystals in bone, inhibiting osteoclast-mediated bone resorption by disrupting the mevalonate pathway within osteoclasts. This reduces bone turnover and increases bone mineral density.
2D Yapı
Cite this structure
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SMILES
CC(O)(P(=O)(O)O)P(=O)(O)O
InChI
InChI=1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9)
Molecular Formula
C2H8O7P2
HBD / HBA
5 / 7
Döndürülebilir Bağlar
2
Ağır Atomlar
11
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
This bisphosphonate medication slows bone breakdown by inhibiting osteoclasts, the cells responsible for dissolving bone tissue. It is used to treat Paget's disease and to prevent bone loss in certain conditions.
Binds to hydroxyapatite crystals in bone, inhibiting osteoclast-mediated bone resorption by disrupting the mevalonate pathway within osteoclasts. This reduces bone turnover and increases bone mineral density.
Yes, Etidronic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL871. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3305. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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