Fedratinib

CHEMBL1287853 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

524.7 g/mol

LogP

4.8

Phase

4

This oral medication blocks JAK2, an enzyme that is overactivated in certain blood cancers, slowing the abnormal growth of blood cells. It is used to treat myelofibrosis and polycythemia vera.

Moleküler Ağırlık

524,7000 g/mol

LogP

4,80

TPSA

117,00 Å²

Lipinski RO5

Geçer

Terapötik Alanlar

Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

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SMILES

Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1

InChI

InChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31)

Molecular Formula

C27H36N6O3S

HBD / HBA

3 / 9

Döndürülebilir Bağlar

11

Ağır Atomlar

37

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

This oral medication blocks JAK2, an enzyme that is overactivated in certain blood cancers, slowing the abnormal growth of blood cells. It is used to treat myelofibrosis and polycythemia vera.

Yes, Fedratinib is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1287853. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 16722836. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Fedratinib PillFYI'da

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Hızlı Veriler

Formül: C27H36N6O3S
Eş Anlamlılar: 1

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.