Givinostat Hydrochloride

CHEMBL6068400 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

457.9 g/mol

LogP

—

Phase

4

A hydrochloride salt form of givinostat with the same therapeutic properties. A histone deacetylase inhibitor that modifies gene expression in abnormal cells, used to treat polycythemia vera and investigated for other blood disorders and Duchenne muscular dystrophy.

Moleküler Ağırlık

457,9000 g/mol

TPSA

90,90 Å²

Terapötik Alanlar

Lymphoma Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

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SMILES

CCN(CC)Cc1ccc2cc(COC(=O)Nc3ccc(C(=O)NO)cc3)ccc2c1.Cl.O

InChI

InChI=1S/C24H27N3O4.ClH.H2O/c1-3-27(4-2)15-17-5-7-21-14-18(6-8-20(21)13-17)16-31-24(29)25-22-11-9-19(10-12-22)23(28)26-30;;/h5-14,30H,3-4,15-16H2,1-2H3,(H,25,29)(H,26,28);1H;1H2

Molecular Formula

C24H28ClN3O4

HBD / HBA

4 / 5

Döndürülebilir Bağlar

9

Ağır Atomlar

32

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

A hydrochloride salt form of givinostat with the same therapeutic properties. A histone deacetylase inhibitor that modifies gene expression in abnormal cells, used to treat polycythemia vera and investigated for other blood disorders and Duchenne muscular dystrophy.

Yes, Givinostat Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6068400. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 10095659. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Formül: C24H28ClN3O4

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.