Hydromorphone Hydrochloride

CHEMBL1237055 Phase 4 Onaylandı Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
321.8 g/mol
LogP
Phase
4

A hydrochloride salt form of hydromorphone, a strong opioid pain reliever used for the management of moderate to severe pain when other analgesics are inadequate. The hydrochloride form is the standard pharmaceutical preparation used in tablets, injectable solutions, and extended-release capsules. As with all potent opioids, risk of respiratory depression, dependence, and misuse must be carefully managed.

Moleküler Ağırlık

321,8000 g/mol

TPSA

49,80 Ų

Terapötik Alanlar

Etki Mekanizması

Semisynthetic mu-opioid receptor agonist approximately 5 times more potent than morphine.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanizma

Semisynthetic mu-opioid receptor agonist approximately 5 times more potent than morphine.

2D Yapı

SVG PNG

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SMILES

CN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@H]3[C@H]1C5.Cl

InChI

InChI=1S/C17H19NO3.ClH/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18;/h2,4,10-11,16,19H,3,5-8H2,1H3;1H/t10-,11+,16-,17-;/m0./s1

Molecular Formula

C17H20ClNO3

HBD / HBA

2 / 4

Döndürülebilir Bağlar

0

Ağır Atomlar

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

A hydrochloride salt form of hydromorphone, a strong opioid pain reliever used for the management of moderate to severe pain when other analgesics are inadequate. The hydrochloride form is the standard pharmaceutical preparation used in tablets, injectable solutions, and extended-release capsules. As with all potent opioids, risk of respiratory depression, dependence, and misuse must be carefully managed.

Semisynthetic mu-opioid receptor agonist approximately 5 times more potent than morphine.

Yes, Hydromorphone Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1237055. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 5462347. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Tıbbi Sorumluluk Reddi

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.