Idarucizumab
This monoclonal antibody fragment is used specifically to reverse the anticoagulant effects of dabigatran (a direct thrombin inhibitor) in emergency situations such as life-threatening bleeding or urgent surgery. It works by binding to dabigatran with very high affinity, neutralizing its blood-thinning activity within minutes. It is given as a single intravenous dose.
Terapötik Alanlar
Etki Mekanizması
As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
This monoclonal antibody fragment is used specifically to reverse the anticoagulant effects of dabigatran (a direct thrombin inhibitor) in emergency situations such as life-threatening bleeding or urgent surgery. It works by binding to dabigatran with very high affinity, neutralizing its blood-thinning activity within minutes. It is given as a single intravenous dose.
As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.
Yes, Idarucizumab is an approved drug. It has reached clinical phase 4. It is classified as a Antibody.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3544996. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
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