Iobenguane Sulfate I 131
This radiolabeled compound is a targeted radiopharmaceutical approved for treating adults with advanced pheochromocytoma or paraganglioma that cannot be removed surgically. After intravenous injection, the compound is taken up by tumor cells, where the iodine-131 radioactivity delivers a lethal dose of radiation locally. Thyroid protective measures are required to prevent radioiodine uptake by the thyroid gland.
Moleküler Ağırlık
656,3000 g/mol
TPSA
212,00 Ų
Etki Mekanizması
Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.
2D Yapı
Cite this structure
Embed this structure
SMILES
N=C(N)NCc1cccc([131I])c1.N=C(N)NCc1cccc([131I])c1.O=S(=O)(O)O
InChI
InChI=1S/2C8H10IN3.H2O4S/c2*9-7-3-1-2-6(4-7)5-12-8(10)11;1-5(2,3)4/h2*1-4H,5H2,(H4,10,11,12);(H2,1,2,3,4)/i2*9+4;
Molecular Formula
C16H22I2N6O4S
HBD / HBA
6 / 6
Döndürülebilir Bağlar
4
Ağır Atomlar
29
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
This radiolabeled compound is a targeted radiopharmaceutical approved for treating adults with advanced pheochromocytoma or paraganglioma that cannot be removed surgically. After intravenous injection, the compound is taken up by tumor cells, where the iodine-131 radioactivity delivers a lethal dose of radiation locally. Thyroid protective measures are required to prevent radioiodine uptake by the thyroid gland.
Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.
Yes, Iobenguane Sulfate I 131 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989511. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 76971242. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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