Meclizine Hydrochloride

CHEMBL3989555 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

481.9 g/mol

LogP

—

Phase

4

A hydrochloride salt form of meclizine, an antihistamine medication used to treat and prevent dizziness, nausea, and vomiting caused by motion sickness and vestibular disorders.

Moleküler Ağırlık

481,9000 g/mol

TPSA

7,50 Å²

Etki Mekanizması

Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanizma

Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.

2D Yapı

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SMILES

Cc1cccc(CN2CCN(C(c3ccccc3)c3ccc(Cl)cc3)CC2)c1.Cl.Cl.O

InChI

InChI=1S/C25H27ClN2.2ClH.H2O/c1-20-6-5-7-21(18-20)19-27-14-16-28(17-15-27)25(22-8-3-2-4-9-22)23-10-12-24(26)13-11-23;;;/h2-13,18,25H,14-17,19H2,1H3;2*1H;1H2

Molecular Formula

C25H31Cl3N2O

HBD / HBA

3 / 3

Döndürülebilir Bağlar

5

Ağır Atomlar

31

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

A hydrochloride salt form of meclizine, an antihistamine medication used to treat and prevent dizziness, nausea, and vomiting caused by motion sickness and vestibular disorders.

Competitively blocks histamine H1 receptors on effector cells, preventing histamine-mediated vasodilation, increased vascular permeability, bronchoconstriction, and pruritus. First-generation agents also cross the blood-brain barrier, causing sedation.

Yes, Meclizine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989555. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 173612. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Meclizine Hydrochloride PillFYI'da

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Hızlı Veriler

Formül: C25H31Cl3N2O
Eş Anlamlılar: 20

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Tıbbi Sorumluluk Reddi

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.

Meclizine Hydrochloride

Etki Mekanizması

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

Cite this structure

Embed this structure

No targets recorded

No interactions recorded

No side effects recorded

Sıkça Sorulan Sorular

References & Data Sources

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