Niclosamide
Originally developed as an antiparasitic, this drug is being studied for its ability to interfere with signaling pathways that help cancer cells survive.
Moleküler Ağırlık
327,1200 g/mol
LogP
4,00
TPSA
95,20 Ų
Lipinski RO5
Geçer
Terapötik Alanlar
Etki Mekanizması
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.
2D Yapı
Cite this structure
Embed this structure
SMILES
O=C(Nc1ccc([N+](=O)[O-])cc1Cl)c1cc(Cl)ccc1O
InChI
InChI=1S/C13H8Cl2N2O4/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15/h1-6,18H,(H,16,19)
Molecular Formula
C13H8Cl2N2O4
HBD / HBA
2 / 4
Döndürülebilir Bağlar
2
Ağır Atomlar
21
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
Originally developed as an antiparasitic, this drug is being studied for its ability to interfere with signaling pathways that help cancer cells survive.
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.
Yes, Niclosamide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1448. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4477. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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