Nortriptyline

CHEMBL445 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

263.4 g/mol

LogP

4.5

Phase

4

A tricyclic antidepressant that increases levels of serotonin and norepinephrine in the brain.

Moleküler Ağırlık

263,4000 g/mol

LogP

4,50

TPSA

12,00 Å²

Lipinski RO5

Geçer

Terapötik Alanlar

Endometriosis Pain Management Migraine Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Gastroesophageal Reflux Disease Psoriasis Major Depressive Disorder Atopic Dermatitis Chronic Pain

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

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SMILES

CNCCC=C1c2ccccc2CCc2ccccc21

InChI

InChI=1S/C19H21N/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19/h2-5,7-11,20H,6,12-14H2,1H3

Molecular Formula

C19H21N

HBD / HBA

1 / 1

Döndürülebilir Bağlar

3

Ağır Atomlar

20

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

A tricyclic antidepressant that increases levels of serotonin and norepinephrine in the brain.

Yes, Nortriptyline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL445. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4543. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Hızlı Veriler

Formül: C19H21N
Eş Anlamlılar: 2

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.