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What is Pegaptanib Sodium used for?

A sodium salt form of pegaptanib, an RNA aptamer that binds and inhibits vascular endothelial growth factor (VEGF-165), used to treat neovascular (wet) age-related macular degeneration. By blocking abnormal blood vessel growth in the retina, it helps preserve vision.

How does Pegaptanib Sodium work?

Inhibits vascular endothelial growth factor (VEGF) signaling, blocking angiogenesis (new blood vessel formation) that tumors require for growth and metastasis.

Is Pegaptanib Sodium an approved drug?

Yes, Pegaptanib Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

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References & Data Sources

• ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201421. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.