Pemafibrate

CHEMBL247951 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

490.5 g/mol

LogP

6.2

Phase

4

A selective peroxisome proliferator-activated receptor alpha (PPARα) agonist used in Japan to lower elevated triglyceride levels in patients with dyslipidemia. It is more selective than older fibrates, potentially offering a more favorable safety profile.

Moleküler Ağırlık

490,5000 g/mol

LogP

6,20

TPSA

94,30 Å²

Lipinski RO5

Geçer

Terapötik Alanlar

Non-Alcoholic Fatty Liver Disease Hyperlipidemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

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SMILES

CC[C@@H](Oc1cccc(CN(CCCOc2ccc(OC)cc2)c2nc3ccccc3o2)c1)C(=O)O

InChI

InChI=1S/C28H30N2O6/c1-3-25(27(31)32)35-23-9-6-8-20(18-23)19-30(28-29-24-10-4-5-11-26(24)36-28)16-7-17-34-22-14-12-21(33-2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)/t25-/m1/s1

Molecular Formula

C28H30N2O6

HBD / HBA

1 / 8

Döndürülebilir Bağlar

13

Ağır Atomlar

36

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

A selective peroxisome proliferator-activated receptor alpha (PPARα) agonist used in Japan to lower elevated triglyceride levels in patients with dyslipidemia. It is more selective than older fibrates, potentially offering a more favorable safety profile.

Yes, Pemafibrate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL247951. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 11526038. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Formül: C28H30N2O6

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.