Pemoline

CHEMBL1177 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

176.2 g/mol

LogP

0.9

Phase

4

A central nervous system stimulant formerly used to treat attention deficit hyperactivity disorder (ADHD), withdrawn from most markets due to serious liver toxicity. It worked by increasing dopamine activity but caused hepatic failure in some patients.

Moleküler Ağırlık

176,1700 g/mol

LogP

0,90

TPSA

64,70 Å²

Lipinski RO5

Geçer

Terapötik Alanlar

Type 2 Diabetes

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

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SMILES

NC1=NC(=O)C(c2ccccc2)O1

InChI

InChI=1S/C9H8N2O2/c10-9-11-8(12)7(13-9)6-4-2-1-3-5-6/h1-5,7H,(H2,10,11,12)

Molecular Formula

C9H8N2O2

HBD / HBA

1 / 2

Döndürülebilir Bağlar

1

Ağır Atomlar

13

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

A central nervous system stimulant formerly used to treat attention deficit hyperactivity disorder (ADHD), withdrawn from most markets due to serious liver toxicity. It worked by increasing dopamine activity but caused hepatic failure in some patients.

Yes, Pemoline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1177. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4723. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Hızlı Veriler

Formül: C9H8N2O2

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.