Potassium Perchlorate
Potassium perchlorate is an inorganic salt that acts as a competitive inhibitor of the sodium-iodide symporter (NIS), blocking iodide uptake into the thyroid gland and thereby reducing thyroid hormone synthesis. It is used for the treatment of hyperthyroidism and thyrotoxicosis, and has been used to prevent iodide-induced hyperthyroidism during iodinated contrast administration.
Moleküler Ağırlık
138,5500 g/mol
TPSA
74,30 Ų
Terapötik Alanlar
Etki Mekanizması
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
2D Yapı
Cite this structure
Embed this structure
SMILES
[K+].[O-][Cl+3]([O-])([O-])[O-]
InChI
InChI=1S/ClHO4.K/c2-1(3,4)5;/h(H,2,3,4,5);/q;+1/p-1
Molecular Formula
ClKO4
HBD / HBA
- / 4
Döndürülebilir Bağlar
0
Ağır Atomlar
6
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
Potassium perchlorate is an inorganic salt that acts as a competitive inhibitor of the sodium-iodide symporter (NIS), blocking iodide uptake into the thyroid gland and thereby reducing thyroid hormone synthesis. It is used for the treatment of hyperthyroidism and thyrotoxicosis, and has been used to prevent iodide-induced hyperthyroidism during iodinated contrast administration.
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Yes, Potassium Perchlorate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200696. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 516900. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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