Pyritinol
Pyritinol is a semi-synthetic derivative of pyridoxine (vitamin B6) that is believed to enhance cholinergic neurotransmission and cerebral glucose metabolism, and has been used as a nootropic and neuroprotective agent. It was used for the treatment of cognitive impairment and has been investigated in anxiety disorders, schizophrenia, and rheumatoid arthritis, though it was withdrawn in some countries due to rare but serious adverse effects.
Moleküler Ağırlık
368,5000 g/mol
LogP
1,20
TPSA
157,00 Ų
Lipinski RO5
Geçer
Terapötik Alanlar
Etki Mekanizması
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
2D Yapı
Cite this structure
Embed this structure
SMILES
Cc1ncc(CSSCc2cnc(C)c(O)c2CO)c(CO)c1O
InChI
InChI=1S/C16H20N2O4S2/c1-9-15(21)13(5-19)11(3-17-9)7-23-24-8-12-4-18-10(2)16(22)14(12)6-20/h3-4,19-22H,5-8H2,1-2H3
Molecular Formula
C16H20N2O4S2
HBD / HBA
4 / 8
Döndürülebilir Bağlar
7
Ağır Atomlar
24
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
Pyritinol is a semi-synthetic derivative of pyridoxine (vitamin B6) that is believed to enhance cholinergic neurotransmission and cerebral glucose metabolism, and has been used as a nootropic and neuroprotective agent. It was used for the treatment of cognitive impairment and has been investigated in anxiety disorders, schizophrenia, and rheumatoid arthritis, though it was withdrawn in some countries due to rare but serious adverse effects.
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Yes, Pyritinol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL488093. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 14190. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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