Reboxetine
A selective norepinephrine reuptake inhibitor used outside the United States to treat major depressive disorder by increasing norepinephrine levels in the brain. It differs from most antidepressants by having minimal effect on serotonin reuptake.
Moleküler Ağırlık
313,4000 g/mol
LogP
3,00
TPSA
39,70 Ų
Lipinski RO5
Geçer
Terapötik Alanlar
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Yapı
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SMILES
CCOc1ccccc1OC(c1ccccc1)C1CNCCO1
InChI
InChI=1S/C19H23NO3/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18/h3-11,18-20H,2,12-14H2,1H3
Molecular Formula
C19H23NO3
HBD / HBA
1 / 4
Döndürülebilir Bağlar
6
Ağır Atomlar
23
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
A selective norepinephrine reuptake inhibitor used outside the United States to treat major depressive disorder by increasing norepinephrine levels in the brain. It differs from most antidepressants by having minimal effect on serotonin reuptake.
Yes, Reboxetine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL14370. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 127151. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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