Sulfaguanidine

CHEMBL338802 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

214.2 g/mol

LogP

-0.7

Phase

4

Sulfaguanidine is a sulfonamide antibiotic that is poorly absorbed from the gastrointestinal tract, achieving high local concentrations in the gut lumen, used historically for intestinal bacterial infections, preoperative bowel preparation, and bacillary dysentery. Its poor systemic absorption limits both its utility for systemic infections and its systemic adverse effects. It has been largely replaced by trimethoprim-sulfamethoxazole and other agents for intestinal infections.

Moleküler Ağırlık

214,2500 g/mol

LogP

-0,70

TPSA

133,00 Å²

Lipinski RO5

Geçer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

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SMILES

N=C(N)NS(=O)(=O)c1ccc(N)cc1

InChI

InChI=1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11)

Molecular Formula

C7H10N4O2S

HBD / HBA

3 / 4

Döndürülebilir Bağlar

2

Ağır Atomlar

14

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

Sulfaguanidine is a sulfonamide antibiotic that is poorly absorbed from the gastrointestinal tract, achieving high local concentrations in the gut lumen, used historically for intestinal bacterial infections, preoperative bowel preparation, and bacillary dysentery. Its poor systemic absorption limits both its utility for systemic infections and its systemic adverse effects. It has been largely replaced by trimethoprim-sulfamethoxazole and other agents for intestinal infections.

Yes, Sulfaguanidine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL338802. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5324. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Formül: C7H10N4O2S

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.