Tepotinib Hydrochloride

CHEMBL4594292 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

547.0 g/mol

LogP

—

Phase

4

Tepotinib hydrochloride is the hydrochloride salt form of tepotinib, a selective MET tyrosine kinase inhibitor approved for METex14-mutated non-small cell lung cancer. See tepotinib for complete pharmacological details. This salt formulation is used in approved oral tablet preparations.

Moleküler Ağırlık

547,0000 g/mol

TPSA

95,70 Å²

Terapötik Alanlar

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Breast Cancer Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

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SMILES

CN1CCC(COc2cnc(-c3cccc(Cn4nc(-c5cccc(C#N)c5)ccc4=O)c3)nc2)CC1.Cl.O

InChI

InChI=1S/C29H28N6O2.ClH.H2O/c1-34-12-10-21(11-13-34)20-37-26-17-31-29(32-18-26)25-7-3-5-23(15-25)19-35-28(36)9-8-27(33-35)24-6-2-4-22(14-24)16-30;;/h2-9,14-15,17-18,21H,10-13,19-20H2,1H3;1H;1H2

Molecular Formula

C29H31ClN6O3

HBD / HBA

2 / 8

Döndürülebilir Bağlar

7

Ağır Atomlar

39

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

Tepotinib hydrochloride is the hydrochloride salt form of tepotinib, a selective MET tyrosine kinase inhibitor approved for METex14-mutated non-small cell lung cancer. See tepotinib for complete pharmacological details. This salt formulation is used in approved oral tablet preparations.

Yes, Tepotinib Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4594292. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 46700774. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Hızlı Veriler

Formül: C29H31ClN6O3
Eş Anlamlılar: 1

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.