Tolmetin

CHEMBL1020 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

257.3 g/mol

LogP

2.8

Phase

4

This nonsteroidal anti-inflammatory drug (NSAID) is used to relieve pain, tenderness, swelling, and stiffness caused by arthritis, including both rheumatoid and osteoarthritis. It works by blocking enzymes (COX-1 and COX-2) that produce prostaglandins, which are chemicals involved in pain and inflammation. Like all NSAIDs, it should be used at the lowest effective dose for the shortest time to reduce the risk of stomach, kidney, and heart side effects.

Moleküler Ağırlık

257,2800 g/mol

LogP

2,80

TPSA

59,30 Å²

Lipinski RO5

Geçer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

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SMILES

Cc1ccc(C(=O)c2ccc(CC(=O)O)n2C)cc1

InChI

InChI=1S/C15H15NO3/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18/h3-8H,9H2,1-2H3,(H,17,18)

Molecular Formula

C15H15NO3

HBD / HBA

1 / 3

Döndürülebilir Bağlar

4

Ağır Atomlar

19

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

This nonsteroidal anti-inflammatory drug (NSAID) is used to relieve pain, tenderness, swelling, and stiffness caused by arthritis, including both rheumatoid and osteoarthritis. It works by blocking enzymes (COX-1 and COX-2) that produce prostaglandins, which are chemicals involved in pain and inflammation. Like all NSAIDs, it should be used at the lowest effective dose for the shortest time to reduce the risk of stomach, kidney, and heart side effects.

Yes, Tolmetin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1020. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5509. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Hızlı Veriler

Formül: C15H15NO3
Eş Anlamlılar: 1

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.