Acetaminophen vs Ibuprofen

## Acetaminophen vs Ibuprofen: Overview

This comparison examines the pharmacological differences between **Acetaminophen** and **Ibuprofen**.

## Mechanism of Action

**Acetaminophen**: Inhibits prostaglandin synthesis in the CNS and peripherally blocks pain impulse generation.

**Ibuprofen**: Non-selective COX inhibitor reducing prostaglandin synthesis.

## Pharmacokinetics

**Half-life**: Acetaminophen — 1-4 hours; Ibuprofen — 2-4 hours.

## Chemical Properties

**Molecular Formula**: Acetaminophen — C8H9NO2; Ibuprofen — C13H18O2.

**Molecular Weight**: Acetaminophen — 151.1630 g/mol; Ibuprofen — 206.2810 g/mol.

**Type**: Acetaminophen — Small molecule; Ibuprofen — Small molecule.