Acyclovir vs Tofacitinib

## Acyclovir vs Tofacitinib: Overview

This comparison examines the pharmacological differences between **Acyclovir** and **Tofacitinib**.

## Mechanism of Action

**Acyclovir**: Guanosine analogue inhibiting viral DNA polymerase.

**Tofacitinib**: Pan-JAK inhibitor with preference for JAK1 and JAK3 blocking pro-inflammatory cytokine signaling.

## Pharmacokinetics

**Half-life**: Acyclovir — 2.5-3.3 hours; Tofacitinib — 3.2 hours.

## Chemical Properties

**Molecular Formula**: Acyclovir — C8H11N5O3; Tofacitinib — C16H20N6O.

**Molecular Weight**: Acyclovir — 225.2050 g/mol; Tofacitinib — 312.3700 g/mol.

**Type**: Acyclovir — Small molecule; Tofacitinib — Small molecule.