Aspirin vs Ibuprofen

## Aspirin vs Ibuprofen: Overview

This comparison examines the pharmacological differences between **Aspirin** and **Ibuprofen**.

## Mechanism of Action

**Aspirin**: Irreversibly inhibits cyclooxygenase-1 and -2.

**Ibuprofen**: Non-selective COX inhibitor reducing prostaglandin synthesis.

## Pharmacokinetics

**Half-life**: Aspirin — 2-3 hours; Ibuprofen — 2-4 hours.

## Chemical Properties

**Molecular Formula**: Aspirin — C9H8O4; Ibuprofen — C13H18O2.

**Molecular Weight**: Aspirin — 180.1580 g/mol; Ibuprofen — 206.2810 g/mol.

**Type**: Aspirin — Small molecule; Ibuprofen — Small molecule.