Azithromycin vs Fluconazole

## Azithromycin vs Fluconazole: Overview

This comparison examines the pharmacological differences between **Azithromycin** and **Fluconazole**.

## Mechanism of Action

**Azithromycin**: Binds 50S ribosomal subunit, inhibiting bacterial protein synthesis.

**Fluconazole**: Inhibits fungal CYP51 (lanosterol 14-alpha-demethylase).

## Pharmacokinetics

**Half-life**: Azithromycin — 68 hours; Fluconazole — 30 hours.

## Chemical Properties

**Molecular Formula**: Azithromycin — C38H72N2O12; Fluconazole — C13H12F2N6O.

**Molecular Weight**: Azithromycin — 748.9840 g/mol; Fluconazole — 306.2710 g/mol.

**Type**: Azithromycin — Small molecule; Fluconazole — Small molecule.