Canagliflozin vs Dapagliflozin

## Canagliflozin vs Dapagliflozin: Overview

This comparison examines the pharmacological differences between **Canagliflozin** and **Dapagliflozin**.

## Mechanism of Action

**Canagliflozin**: Selective SGLT2 inhibitor reducing renal glucose reabsorption and lowering blood glucose.

**Dapagliflozin**: Selective SGLT2 inhibitor reducing renal glucose and sodium reabsorption.

## Pharmacokinetics

**Half-life**: Canagliflozin — 10.6 hours; Dapagliflozin — 12.9 hours.

## Chemical Properties

**Molecular Formula**: Canagliflozin — C24H25FO5S; Dapagliflozin — C21H25ClO6.

**Molecular Weight**: Canagliflozin — 444.5170 g/mol; Dapagliflozin — 408.8730 g/mol.

**Type**: Canagliflozin — Small molecule; Dapagliflozin — Small molecule.