Celecoxib vs Upadacitinib

## Celecoxib vs Upadacitinib: Overview

This comparison examines the pharmacological differences between **Celecoxib** and **Upadacitinib**.

## Mechanism of Action

**Celecoxib**: Selective COX-2 inhibitor.

**Upadacitinib**: Selective JAK1 inhibitor reducing signaling from cytokines implicated in autoimmune diseases.

## Pharmacokinetics

**Half-life**: Celecoxib — 11 hours; Upadacitinib — 9-14 hours.

## Chemical Properties

**Molecular Formula**: Celecoxib — C17H14F3N3O2S; Upadacitinib — C17H19F3N6O.

**Molecular Weight**: Celecoxib — 381.3730 g/mol; Upadacitinib — 380.3700 g/mol.

**Type**: Celecoxib — Small molecule; Upadacitinib — Small molecule.