Cetirizine vs Methotrexate

## Cetirizine vs Methotrexate: Overview

This comparison examines the pharmacological differences between **Cetirizine** and **Methotrexate**.

## Mechanism of Action

**Cetirizine**: Second-generation H1 antihistamine.

**Methotrexate**: Dihydrofolate reductase inhibitor.

## Pharmacokinetics

**Half-life**: Cetirizine — 6.5-10 hours; Methotrexate — 3-10 hours.

## Chemical Properties

**Molecular Formula**: Cetirizine — C21H25ClN2O3; Methotrexate — C20H22N8O5.

**Molecular Weight**: Cetirizine — 388.8900 g/mol; Methotrexate — 454.4400 g/mol.

**Type**: Cetirizine — Small molecule; Methotrexate — Small molecule.