Citalopram vs Methotrexate

## Citalopram vs Methotrexate: Overview

This comparison examines the pharmacological differences between **Citalopram** and **Methotrexate**.

## Mechanism of Action

**Citalopram**: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

**Methotrexate**: Dihydrofolate reductase inhibitor.

## Pharmacokinetics

**Half-life**: Citalopram — 35 hours; Methotrexate — 3-10 hours.

## Chemical Properties

**Molecular Formula**: Citalopram — C20H21FN2O; Methotrexate — C20H22N8O5.

**Molecular Weight**: Citalopram — 324.3920 g/mol; Methotrexate — 454.4400 g/mol.

**Type**: Citalopram — Small molecule; Methotrexate — Small molecule.