Citalopram vs Osimertinib

## Citalopram vs Osimertinib: Overview

This comparison examines the pharmacological differences between **Citalopram** and **Osimertinib**.

## Mechanism of Action

**Citalopram**: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

**Osimertinib**: Third-generation irreversible EGFR TKI targeting T790M resistance mutation and activating mutations.

## Pharmacokinetics

**Half-life**: Citalopram — 35 hours; Osimertinib — 48 hours.

## Chemical Properties

**Molecular Formula**: Citalopram — C20H21FN2O; Osimertinib — C28H33N7O2.

**Molecular Weight**: Citalopram — 324.3920 g/mol; Osimertinib — 499.6050 g/mol.

**Type**: Citalopram — Small molecule; Osimertinib — Small molecule.