Dexamethasone vs Upadacitinib

## Dexamethasone vs Upadacitinib: Overview

This comparison examines the pharmacological differences between **Dexamethasone** and **Upadacitinib**.

## Mechanism of Action

**Dexamethasone**: Potent synthetic glucocorticoid.

**Upadacitinib**: Selective JAK1 inhibitor reducing signaling from cytokines implicated in autoimmune diseases.

## Pharmacokinetics

**Half-life**: Dexamethasone — 36-54 hours; Upadacitinib — 9-14 hours.

## Chemical Properties

**Molecular Formula**: Dexamethasone — C22H29FO5; Upadacitinib — C17H19F3N6O.

**Molecular Weight**: Dexamethasone — 392.4610 g/mol; Upadacitinib — 380.3700 g/mol.

**Type**: Dexamethasone — Small molecule; Upadacitinib — Small molecule.