Diazepam vs Hydrochlorothiazide

## Diazepam vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between **Diazepam** and **Hydrochlorothiazide**.

## Mechanism of Action

**Diazepam**: Positive allosteric modulator of GABA-A receptors.

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

## Pharmacokinetics

**Half-life**: Diazepam — 20-100 hours; Hydrochlorothiazide — 6-15 hours.

## Chemical Properties

**Molecular Formula**: Diazepam — C16H13ClN2O; Hydrochlorothiazide — C7H8ClN3O4S2.

**Molecular Weight**: Diazepam — 284.7400 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

**Type**: Diazepam — Small molecule; Hydrochlorothiazide — Small molecule.