Diazepam vs Sildenafil

## Diazepam vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Diazepam** and **Sildenafil**.

## Mechanism of Action

**Diazepam**: Positive allosteric modulator of GABA-A receptors.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Diazepam — 20-100 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Diazepam — C16H13ClN2O; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Diazepam — 284.7400 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Diazepam — Small molecule; Sildenafil — Small molecule.