Digoxin vs Simvastatin

## Digoxin vs Simvastatin: Overview

This comparison examines the pharmacological differences between **Digoxin** and **Simvastatin**.

## Mechanism of Action

**Digoxin**: Inhibits Na+/K+-ATPase, increasing intracellular calcium.

**Simvastatin**: Prodrug converted to active form that inhibits HMG-CoA reductase.

## Pharmacokinetics

**Half-life**: Digoxin — 36-48 hours; Simvastatin — 2 hours.

## Chemical Properties

**Molecular Formula**: Digoxin — C41H64O14; Simvastatin — C25H38O5.

**Molecular Weight**: Digoxin — 780.9430 g/mol; Simvastatin — 418.5700 g/mol.

**Type**: Digoxin — Small molecule; Simvastatin — Small molecule.