Doxycycline vs Trimethoprim

## Doxycycline vs Trimethoprim: Overview

This comparison examines the pharmacological differences between **Doxycycline** and **Trimethoprim**.

## Mechanism of Action

**Doxycycline**: Inhibits bacterial protein synthesis by binding 30S ribosomal subunit.

**Trimethoprim**: Dihydrofolate reductase inhibitor (bacterial selective).

## Pharmacokinetics

**Half-life**: Doxycycline — 18-22 hours; Trimethoprim — 8-10 hours.

## Chemical Properties

**Molecular Formula**: Doxycycline — C22H24N2O8; Trimethoprim — C14H18N4O3.

**Molecular Weight**: Doxycycline — 444.4350 g/mol; Trimethoprim — 290.3180 g/mol.

**Type**: Doxycycline — Small molecule; Trimethoprim — Small molecule.