Empagliflozin vs Tofacitinib

## Empagliflozin vs Tofacitinib: Overview

This comparison examines the pharmacological differences between **Empagliflozin** and **Tofacitinib**.

## Mechanism of Action

**Empagliflozin**: Selective SGLT2 inhibitor reducing renal glucose reabsorption.

**Tofacitinib**: Pan-JAK inhibitor with preference for JAK1 and JAK3 blocking pro-inflammatory cytokine signaling.

## Pharmacokinetics

**Half-life**: Empagliflozin — 12.4 hours; Tofacitinib — 3.2 hours.

## Chemical Properties

**Molecular Formula**: Empagliflozin — C23H27ClO7; Tofacitinib — C16H20N6O.

**Molecular Weight**: Empagliflozin — 450.9100 g/mol; Tofacitinib — 312.3700 g/mol.

**Type**: Empagliflozin — Small molecule; Tofacitinib — Small molecule.