Enalapril vs Sitagliptin

## Enalapril vs Sitagliptin: Overview

This comparison examines the pharmacological differences between **Enalapril** and **Sitagliptin**.

## Mechanism of Action

**Enalapril**: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

**Sitagliptin**: DPP-4 inhibitor increasing incretin levels.

## Pharmacokinetics

**Half-life**: Enalapril — 11 hours; Sitagliptin — 12.4 hours.

## Chemical Properties

**Molecular Formula**: Enalapril — C20H28N2O5; Sitagliptin — C16H15F6N5O.

**Molecular Weight**: Enalapril — 376.4470 g/mol; Sitagliptin — 407.3140 g/mol.

**Type**: Enalapril — Small molecule; Sitagliptin — Small molecule.