Erlotinib vs Metformin

## Erlotinib vs Metformin: Overview

This comparison examines the pharmacological differences between **Erlotinib** and **Metformin**.

## Mechanism of Action

**Erlotinib**: Reversible inhibitor of EGFR (HER1) tyrosine kinase, blocking autophosphorylation.

**Metformin**: Activates AMP-activated protein kinase, decreasing hepatic glucose production.

## Pharmacokinetics

**Half-life**: Erlotinib — 36 hours; Metformin — 4-9 hours.

## Chemical Properties

**Molecular Formula**: Erlotinib — C22H23N3O4; Metformin — C4H11N5.

**Molecular Weight**: Erlotinib — 393.4380 g/mol; Metformin — 129.1640 g/mol.

**Type**: Erlotinib — Small molecule; Metformin — Small molecule.