Hydrochlorothiazide vs Montelukast

## Hydrochlorothiazide vs Montelukast: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Montelukast**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Montelukast**: Selective leukotriene D4 receptor antagonist.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Montelukast — 2.7-5.5 hours.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Montelukast — C35H36ClNO3S.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Montelukast — 586.1800 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Montelukast — Small molecule.