Hydrochlorothiazide vs Nitroglycerin

## Hydrochlorothiazide vs Nitroglycerin: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Nitroglycerin**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Nitroglycerin**: Nitric oxide donor causing venous and arterial vasodilation.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Nitroglycerin — 1-4 minutes.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Nitroglycerin — C3H5N3O9.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Nitroglycerin — 227.0870 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Nitroglycerin — Small molecule.