Loratadine vs Ondansetron

## Loratadine vs Ondansetron: Overview

This comparison examines the pharmacological differences between **Loratadine** and **Ondansetron**.

## Mechanism of Action

**Loratadine**: Second-generation H1 antihistamine with minimal CNS effects.

**Ondansetron**: Selective 5-HT3 receptor antagonist.

## Pharmacokinetics

**Half-life**: Loratadine — 8 hours; Ondansetron — 3-5 hours.

## Chemical Properties

**Molecular Formula**: Loratadine — C22H23ClN2O2; Ondansetron — C18H19N3O.

**Molecular Weight**: Loratadine — 382.8800 g/mol; Ondansetron — 293.3660 g/mol.

**Type**: Loratadine — Small molecule; Ondansetron — Small molecule.