Loratadine vs Spironolactone

## Loratadine vs Spironolactone: Overview

This comparison examines the pharmacological differences between **Loratadine** and **Spironolactone**.

## Mechanism of Action

**Loratadine**: Second-generation H1 antihistamine with minimal CNS effects.

**Spironolactone**: Mineralocorticoid receptor antagonist.

## Pharmacokinetics

**Half-life**: Loratadine — 8 hours; Spironolactone — 1.4 hours.

## Chemical Properties

**Molecular Formula**: Loratadine — C22H23ClN2O2; Spironolactone — C24H32O4S.

**Molecular Weight**: Loratadine — 382.8800 g/mol; Spironolactone — 416.5740 g/mol.

**Type**: Loratadine — Small molecule; Spironolactone — Small molecule.