Loratadine vs Sumatriptan

## Loratadine vs Sumatriptan: Overview

This comparison examines the pharmacological differences between **Loratadine** and **Sumatriptan**.

## Mechanism of Action

**Loratadine**: Second-generation H1 antihistamine with minimal CNS effects.

**Sumatriptan**: Selective 5-HT1B/1D receptor agonist.

## Pharmacokinetics

**Half-life**: Loratadine — 8 hours; Sumatriptan — 2.5 hours.

## Chemical Properties

**Molecular Formula**: Loratadine — C22H23ClN2O2; Sumatriptan — C14H21N3O2S.

**Molecular Weight**: Loratadine — 382.8800 g/mol; Sumatriptan — 295.4020 g/mol.

**Type**: Loratadine — Small molecule; Sumatriptan — Small molecule.