Lorazepam vs Sildenafil

## Lorazepam vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Lorazepam** and **Sildenafil**.

## Mechanism of Action

**Lorazepam**: Intermediate-acting benzodiazepine enhancing GABA-A receptor chloride conductance.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Lorazepam — 10-20 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Lorazepam — C15H10Cl2N2O2; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Lorazepam — 321.1580 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Lorazepam — Small molecule; Sildenafil — Small molecule.