Losartan vs Telmisartan

## Losartan vs Telmisartan: Overview

This comparison examines the pharmacological differences between **Losartan** and **Telmisartan**.

## Mechanism of Action

**Losartan**: Angiotensin II receptor type 1 antagonist.

**Telmisartan**: Selective angiotensin II type 1 receptor antagonist; also a partial PPAR-gamma agonist.

## Pharmacokinetics

**Half-life**: Losartan — 2 hours; Telmisartan — 24 hours.

## Chemical Properties

**Molecular Formula**: Losartan — C22H23ClN6O; Telmisartan — C33H30N4O2.

**Molecular Weight**: Losartan — 422.9200 g/mol; Telmisartan — 514.6230 g/mol.

**Type**: Losartan — Small molecule; Telmisartan — Small molecule.