Lovastatin vs Metformin

## Lovastatin vs Metformin: Overview

This comparison examines the pharmacological differences between **Lovastatin** and **Metformin**.

## Mechanism of Action

**Lovastatin**: First naturally derived statin; prodrug hydrolyzed to active beta-hydroxy acid inhibiting HMG-CoA reductase.

**Metformin**: Activates AMP-activated protein kinase, decreasing hepatic glucose production.

## Pharmacokinetics

**Half-life**: Lovastatin — 2-3 hours; Metformin — 4-9 hours.

## Chemical Properties

**Molecular Formula**: Lovastatin — C24H36O5; Metformin — C4H11N5.

**Molecular Weight**: Lovastatin — 404.5390 g/mol; Metformin — 129.1640 g/mol.

**Type**: Lovastatin — Small molecule; Metformin — Small molecule.