Paroxetine vs Trazodone

## Paroxetine vs Trazodone: Overview

This comparison examines the pharmacological differences between **Paroxetine** and **Trazodone**.

## Mechanism of Action

**Paroxetine**: Potent selective serotonin reuptake inhibitor with additional muscarinic and NE reuptake inhibition.

**Trazodone**: Serotonin antagonist and reuptake inhibitor (SARI).

## Pharmacokinetics

**Half-life**: Paroxetine — 21 hours; Trazodone — 5-9 hours.

## Chemical Properties

**Molecular Formula**: Paroxetine — C19H20FNO3; Trazodone — C19H22ClN5O.

**Molecular Weight**: Paroxetine — 329.3730 g/mol; Trazodone — 371.8640 g/mol.

**Type**: Paroxetine — Small molecule; Trazodone — Small molecule.