Rituximab vs Semaglutide

## Rituximab vs Semaglutide: Overview

This comparison examines the pharmacological differences between **Rituximab** and **Semaglutide**.

## Mechanism of Action

**Rituximab**: Chimeric anti-CD20 IgG1 monoclonal antibody inducing B-cell depletion via CDC, ADCC, and apoptosis.

**Semaglutide**: GLP-1 receptor agonist with enhanced albumin binding for extended action.

## Pharmacokinetics

**Half-life**: Rituximab — 22 days; Semaglutide — 7 days.

## Chemical Properties

**Type**: Rituximab — Antibody; Semaglutide — Protein.