Sildenafil vs Telmisartan

## Sildenafil vs Telmisartan: Overview

This comparison examines the pharmacological differences between **Sildenafil** and **Telmisartan**.

## Mechanism of Action

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

**Telmisartan**: Selective angiotensin II type 1 receptor antagonist; also a partial PPAR-gamma agonist.

## Pharmacokinetics

**Half-life**: Sildenafil — 4 hours; Telmisartan — 24 hours.

## Chemical Properties

**Molecular Formula**: Sildenafil — C22H30N6O4S; Telmisartan — C33H30N4O2.

**Molecular Weight**: Sildenafil — 474.5800 g/mol; Telmisartan — 514.6230 g/mol.

**Type**: Sildenafil — Small molecule; Telmisartan — Small molecule.