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Almotriptan

CHEMBL1505 Phase 4 已批准 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
335.5 g/mol
LogP
1.6
Phase
4

A triptan medication that relieves migraine headaches by binding to serotonin receptors in the brain, causing constriction of dilated blood vessels around the brain and blocking the release of pain-causing substances from nerve endings. It is taken at the onset of a migraine to reduce headache severity and associated symptoms like nausea and light sensitivity.

分子量

335.5000 g/mol

LogP

1.60

TPSA

64.80 Ų

Lipinski 五规则

符合

治疗领域

Cardiovascular Disease Migraine

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

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SMILES

                    
CN(C)CCc1c[nH]c2ccc(CS(=O)(=O)N3CCCC3)cc12

                

                

                
                

                    
InChI

                    
InChI=1S/C17H25N3O2S/c1-19(2)10-7-15-12-18-17-6-5-14(11-16(15)17)13-23(21,22)20-8-3-4-9-20/h5-6,11-12,18H,3-4,7-10,13H2,1-2H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C17H25N3O2S

                    

                    
                    

                        
HBD / HBA

                        
1 / 4

                    

                    
                    

                        
可旋转键数

                        
6

                    

                    
                    
                    

                        
重原子数

                        
23

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
常见问题

                

                    
                    

                        
                        

                            
A triptan medication that relieves migraine headaches by binding to serotonin receptors in the brain, causing constriction of dilated blood vessels around the brain and blocking the release of pain-causing substances from nerve endings. It is taken at the onset of a migraine to reduce headache severity and associated symptoms like nausea and light sensitivity.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Almotriptan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1505.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 123606.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
医疗免责声明

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.