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Azathioprine Sodium

CHEMBL1200400 Phase 4 已批准 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
299.2 g/mol
LogP
—
Phase
4

The sodium salt form of azathioprine for intravenous administration, used in patients who cannot take oral medications to provide the same immunosuppressive effects as the standard formulation.

分子量

299.2500 g/mol

TPSA

129.00 Ų

治疗领域

Cardiovascular Disease Rheumatoid Arthritis Inflammatory Bowel Disease Psoriasis Systemic Lupus Erythematosus Multiple Sclerosis Chronic Kidney Disease Atopic Dermatitis Gout Heart Failure

作用机制

Suppresses the immune system by inhibiting T-cell activation, lymphocyte proliferation, or cytokine production. This prevents immune-mediated tissue damage and graft rejection.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

机制

Suppresses the immune system by inhibiting T-cell activation, lymphocyte proliferation, or cytokine production. This prevents immune-mediated tissue damage and graft rejection.

二维结构

SVG PNG

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SMILES

                    
Cn1cnc([N+](=O)[O-])c1Sc1ncnc2nc[n-]c12.[Na+]

                

                

                
                

                    
InChI

                    
InChI=1S/C9H6N7O2S.Na/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8;/h2-4H,1H3;/q-1;+1

                

                

                

                    
                    

                        
Molecular Formula

                        
C9H6N7NaO2S

                    

                    
                    

                        
HBD / HBA

                        
- / 8

                    

                    
                    

                        
可旋转键数

                        
2

                    

                    
                    
                    

                        
重原子数

                        
20

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
常见问题

                

                    
                    

                        
                        

                            
The sodium salt form of azathioprine for intravenous administration, used in patients who cannot take oral medications to provide the same immunosuppressive effects as the standard formulation.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Suppresses the immune system by inhibiting T-cell activation, lymphocyte proliferation, or cytokine production. This prevents immune-mediated tissue damage and graft rejection.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Azathioprine Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200400.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 11529527.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
医疗免责声明

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.