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Cabotegravir Sodium

CHEMBL3137330 Phase 4 已批准 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
427.3 g/mol
LogP
—
Phase
4

The sodium salt form of cabotegravir, used in injectable long-acting formulations for HIV treatment and prevention. It is administered intramuscularly and provides sustained drug levels over weeks to months. This formulation offers a major improvement in treatment convenience for people living with HIV.

分子量

427.3000 g/mol

TPSA

102.00 Ų

治疗领域

HIV/AIDS

作用机制

Inhibits viral integrase, preventing the insertion of viral DNA into the host cell genome and blocking viral replication.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

机制

Inhibits viral integrase, preventing the insertion of viral DNA into the host cell genome and blocking viral replication.

二维结构

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
C[C@H]1CO[C@@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c([O-])c3C(=O)N12.[Na+]

                

                

                
                

                    
InChI

                    
InChI=1S/C19H17F2N3O5.Na/c1-9-8-29-14-7-23-6-12(16(25)17(26)15(23)19(28)24(9)14)18(27)22-5-10-2-3-11(20)4-13(10)21;/h2-4,6,9,14,26H,5,7-8H2,1H3,(H,22,27);/q;+1/p-1/t9-,14+;/m0./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C19H16F2N3NaO5

                    

                    
                    

                        
HBD / HBA

                        
1 / 8

                    

                    
                    

                        
可旋转键数

                        
3

                    

                    
                    
                    

                        
重原子数

                        
30

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
常见问题

                

                    
                    

                        
                        

                            
The sodium salt form of cabotegravir, used in injectable long-acting formulations for HIV treatment and prevention. It is administered intramuscularly and provides sustained drug levels over weeks to months. This formulation offers a major improvement in treatment convenience for people living with HIV.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Inhibits viral integrase, preventing the insertion of viral DNA into the host cell genome and blocking viral replication.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Cabotegravir Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL3137330.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 46215800.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
医疗免责声明

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.