Codeine Sulfate

CHEMBL4297091 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

750.9 g/mol

LogP

—

Phase

4

The sulfate salt formulation of codeine, an opioid analgesic and antitussive derived from the opium poppy. Like other codeine salts, it requires metabolic conversion to morphine for most of its pain-relieving effects.

分子量

750.9000 g/mol

TPSA

170.00 Å²

治疗领域

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Pain Management Non-Small Cell Lung Cancer Generalized Anxiety Disorder Obesity Lymphoma Breast Cancer Chronic Pain Prostate Cancer Colorectal Cancer Leukemia

作用机制

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

机制

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …

二维结构

SVG PNG

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SMILES

COc1ccc2c3c1O[C@H]1[C@@H](O)C=C[C@H]4[C@@H](C2)N(C)CC[C@@]341.COc1ccc2c3c1O[C@H]1[C@@H](O)C=C[C@H]4[C@@H](C2)N(C)CC[C@@]341.O.O.O.O=S(=O)(O)O

InChI

InChI=1S/2C18H21NO3.H2O4S.3H2O/c2*1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19;1-5(2,3)4;;;/h2*3-6,11-13,17,20H,7-9H2,1-2H3;(H2,1,2,3,4);3*1H2/t2*11-,12+,13-,17-,18-;;;;/m00..../s1

Molecular Formula

C36H50N2O13S

HBD / HBA

7 / 15

可旋转键数

2

重原子数

52

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

The sulfate salt formulation of codeine, an opioid analgesic and antitussive derived from the opium poppy. Like other codeine salts, it requires metabolic conversion to morphine for most of its pain-relieving effects.

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Yes, Codeine Sulfate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4297091. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 21155870. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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结构

快速数据

分子式: C36H50N2O13S

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.